Fluorescein angiography is a photographic technique used for evaluating retinal circulation. During this test, a fluorescent medication is injected into a hand or arm vein. As the medication quickly travels to the eye, digital photographs are taken, which are then analyzed by the physician.
Vascular occlusion, wet macular degeneration, macular edema, diabetic retinopathy, and optic nerve disease all present with an abnormal fluorescent pattern on fluorescein angiography.
Baseline color and black & white photos (fundus photos) of the eyes will be taken using a specialized digital camera. After the photos are taken, the doctor or technician will introduce a pediatric needle into a vein in the arm or hand, and will then inject the medicine. The photographer will immediately start a rapid sequence of photos, followed by photos at longer intervals. The entire sequence takes 5-6 minutes
After administration of ﬂuorescein sodium, discoloration of the skin and urine is common. Skin will attain a temporary yellowish discoloration which usually fades in 6 to 12 hours. Urine becomes bright yellow-green in color, which should fade in 24 to 36 hours.
Due to the bright flashes of light throughout the test, the vision will appear to have a red tint. This resolves within minutes once the test has concluded.
In a small percentage of patients, nausea occurs. This passes quickly, but is sometimes associated with vomiting.
Allergic reactions, including anaphylaxis, are extremely rare. Our office is equipped to treat such a reaction if one were to occur.